Spina bifida is associated with genetic abnormalities including trisomies 13, 18, and 21. Which chromosomal category is implicated?

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Prepare for your Neural Tube Defects Myelomeningocele/Spina Bifida test with detailed flashcards and multiple-choice questions. Each query is supplemented with hints and explanations. Ace your exam with confidence!

Multiple Choice

Spina bifida is associated with genetic abnormalities including trisomies 13, 18, and 21. Which chromosomal category is implicated?

Explanation:
Trisomies are when an extra copy of a chromosome is present, so there are three copies instead of two. When this happens with chromosomes 13, 18, or 21, it leads to Patau, Edwards, and Down syndromes, respectively. Since the scenario mentions trisomies 13, 18, and 21 as associated with spina bifida, the chromosomal category involved is trisomies. In contrast, monosomies involve missing an entire chromosome, deletions remove part of a chromosome, and inversions are rearrangements of a chromosome segment.

Trisomies are when an extra copy of a chromosome is present, so there are three copies instead of two. When this happens with chromosomes 13, 18, or 21, it leads to Patau, Edwards, and Down syndromes, respectively. Since the scenario mentions trisomies 13, 18, and 21 as associated with spina bifida, the chromosomal category involved is trisomies. In contrast, monosomies involve missing an entire chromosome, deletions remove part of a chromosome, and inversions are rearrangements of a chromosome segment.

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